Current Research Awards

JAMES GEAR INTERNATIONAL FELLOWSHIP

APPLICANT

INSTITUTE

PURPOSE

GRANT NO

PAYMENT REF NO

Bhiman Dr J

National Institute for Communicable Diseases

Development of immunogens and immunization regimens for the elicitation of HIV-1 broadly neutralizing antibodies

16/73

PRF Bhiman 16/73

 

RESEARCH

APPLICANT

INSTITUTE

PURPOSE

GRANT NO

PAYMENT REF NO

Abrahams Dr MH

University of Cape Town

Impact of HIV-1 dual infection on the size and composition of the latent viral reservoir

16/01

PRF Abrahams 16/01

Andersson Dr MI

Univ of Stellenbosch

Hepatitis B virus related hepatocellular carcinoma (HCC) in HIV-infected vs HIV-uninfected patients:  What are the differences in HBV and host genetic profiles in liver tissue?

15/02

PRF Andersson 15/02

Anthony Dr CS

University of Cape Town

Development of a full length gene, deep-sequencing strategy to study distal convolving sites in HIV-1

16/02

PRF Anthony 16/02

Basson Dr AE

The National Institute of Communicable Diseases

What are the fitness characteristics of HIV-1 in patients who re-suppress on the same ARV regimen?

14/07

PRF Basson 14/07

Burt Prof F

University of the Free State

Innate signalling induced by Crimean-Congo haemorrhagic fever virus (CCHFV) proteins and Hazara virus as model for CCHFV

15/05

PRF Burt 15/05

Coertse Dr J

University of Pretoria

Pathogenicity studies with zoonotic viruses causing encephalitic diseases in South Africa

16/03

PRF Coertse 16/03

Crowther Prof N

University of the Witwatersrand

Investigation into the effect of HIV viral proteins on endothelial function in the HIV infected population

16/04

PRF Crowther 16/04

De Beer Dr C

University of Stellenbosch

Optimising a screening protocol for respiratory infections in Sudden Unexpected Death in Infancy (SUDI) cases admitted to the Tygerberg Medio-legal Mortuary

15/07

PRF De Beer 15/07

Dias Dr B

The National Institute of Communicable Diseases

An investigation of CD45 genetic variation, expression and activity in differential control of HIV-1 infection

15/08

PRF Dias 15/08

Ditse Dr Z

The National Institute of Communicable Diseases

Characterization of broadly neutralizing antibody responses in HIV-1 subtype C infected children

16/05

PRF Ditse 16/05

Dorfman Dr JR

University of Cape Town

The impact of donor HIV-1 genital tract compartmentalisation on the transmission bottleneck

15/09

PRF Dorfman 15/09

Engelbrecht Prof S

Univ of Stellenbosch

Comprehensive analysis of HIV-1 diversity in different clinics and hospitals in the Eastern Cape Province

15/10

PRF Engelbrecht 15/10

Engelbrecht Prof D

University of Stellenbosch

Role of adaptive changes and co-evolution of HIV-1C protease cleavage site mutations for protease inhibitor resistance and viral fitness

16/06

PRF Engelbrecht 16/06

Glashoff Dr RH

Univ of Stellenbosch

Tim-3 and other inhibitory CD8+ T cell markers in chronic HIV-1 infection: impact of TB co-infection and immune activation

14/76

PRF Glashoff 14/76

Goedhals Dr D

University of the Free State

Characterization of T cell responses to the nonstructural proteins of the M segment in survivors of Crimean-Congo haemorrhagic fever virus (CCHFV) infection

15/11

PRF Goedhals 15/11

Govender Dr Y

University of the Witwatersrand

An investigation into CD26 expression and activity in HIV-1 controllers

16/07

PRF Govender 16/07

Hardie Prof D

University of Cape Town

Molecular characterization of neurotropic measles viruses from patients infected during the 2009/10 epidemic in South Africa

16/08

PRF Hardie 16/08

Hitzeroth Dr II

University of Cape Town

Optimisation of Human papillomavirus (HPV) therapeutic vaccines and pseudovirions production in plants and plant cells

15/12

PRF Hitzeroth 15/12

Horsnell Dr W

University of Cape Town

Nematode infections protect against RSV infection and pathology

15/13

PRF Horsnell 15/13

Ithete Dr NL

Univ of Stellenbosch

Investigating the diversity and viral shedding patterns of coronaviruses circulating in southern African bats

14/11

PRF Ithete 14/11

Ithete Dr NL

Univ of Stellenbosch

Molecular characterisation of novel paramyxoviruses (PVs) identified in South African small mammals

15/15

PRF Ithete 15/15

Jacobs Dr G

Univ of Stellenbosch

Characterization of a putative new complex HIV-1 circulating recombinant form (CRFcpx) identified in South Africa

14/12

PRF Jacobs 14/12

Jacobs Dr GB

University of Stellenbosch

The investigation of the molecular diversity and resistance patterns of HIV in different cohorts in Cameroon

16/09

PRF Jacobs 16/09

Jansen  Van Vuren Dr P

The National Institute of Communicable Diseases

Evaluation of risk of Zika virus transmission by South Africa Aedes aegypti mosquitoes

16/10

PRF Jansen V Vuren 16/10

Jaspan Dr H

University of Cape Town

Effect of maternal microbiome during pregnancy and breastfeeding on infant immunity to Respiratory syncytial viral infections in mice

15/16

PRF Jaspan 15/16

Lassauniere Dr R

The National Institute of Communicable Diseases

HIV-1-specific FcγR-mediated effector functions: the role of host factors

16/11

PRF Lassauniere 16/11

Mann Dr JK

University of KwaZulu-Natal

Impact of immune-driven mutations in HIV-1 reverse transcriptase-integrase on viral fitness and disease progression

16/13

PRF Mann 16/13

Mans Dr J

University of Pretoria

Surveillance and characterisation of major and minor norovirus GII.4 variants in South Africa

15/18

PRF Mans 15/18

Markotter Dr W

Univ of Pretoria

Characterization and pathogenesis of paramyxoviruses detected in bats

14/16

PRF Markotter 14/16

Martin Dr DP

University of Cape Town

Retracing the early phylogeography and evolutionary dynamics of HIV-1 group M viruses

16/14

PRF Martin 16/14

Masson Dr L

University of Cape Town

Proteomic biomarkers of HPV prevalence, acquisition and clearence

16/15

PRF Masson 16/15

Mbulawa Dr Z

University of Cape Town

The natural history of oral human papillomavirus (HPV) infection in South African heterosexually active couples

15/19

PRF Mbulawa 15/19

Mbulawa Dr Z

University of Cape Town

A study of herpes simplex virus-2 on human immunodeficiency virus (HIV) concordant, HIV discordant and HIV-negative heterosexual active couples that were either human papillomavirus positive or negative

16/16

PRF Mbulawa 16/16

Mkhize Dr NN

The National Institute of Communicable Diseases

Exploring the use of soluble HIV-1 envelope trimers to isolate braodly neutralizing antibodies

15/82

PRF Mkhize 15/82

Moore Dr PL

The National Institute of Communicable Diseases

Viral evolution during the development and maturation of the V1V2-directed broadly neutralising antibodies in HIV-1 infected participant CAP256

14/17

PRF Moore 14/17

Morris Prof L

The National Institute of Communicable Diseases

Crystal structure of an HIV-1 V2 reactive antibody

15/83

PRF Morris 15/83

Mufhandu Dr H

Council of Scientific and Industrial Research (CSIR)

Isolation of anti-gp 120,anti-CD4 and anti-p24 aptamers for use as reagents in flow cytometry

16/12

PRF Mufhandu 16/12

Ngcapu Dr S

University of KwaZulu-Natal

Role of vaginal microbiome dybiosis in persistence of human papillomavirus (HPV) infections in young South African women

16/17

PRF Ngcapu 16/17

Nyaga Dr MM

University of the Free State

Genomic investigation of different enteric viruses present in human and animal fecal samples collected in southern Africa, using MiSeq Illumina next generation sequencing and NetoVIR, an NGS-based virus discovery protocol

16/74

PRF Nyaga 16/74

O’Neill Dr HG

University of the Free State

Engineering a recombinant Newcastle Disease Virus (NDV) as a candidate vaccine delivery vector for rotavirus VP7 and NSP4 proteins

16/18

PRF O’Neill 16/18

Page Prof NA

National Institute for Communicable Diseases

The molecular characterization and epidemiology of human astroviruses in selected areas of South Africa

15/22

PRF Page 15/22

Papathanasopoulos Prof MA

University of the Witwatersrand

Acquired antiretroviral drug resistance and immune activation associated with low level viremia in South African patients on antiretroviral therapy

16/19

PRF Papathanasopoulos 16/19

Passmore Dr J

Univ of Cape Town

HPV prevalence during HIV infection in women using IUDs

14/18

PRF Passmore 14/18

Passmore Dr J

University of Cape Town

Role of vaginal bacteriophages in emergence of bacterial vaginosis (BV) and modulating the microbiome: controlable viral strategies to decrease risk for HIV infection in women

15/23

PRF Passmore 15/23

Paweska Prof J

The National Institute of Communicable Diseases

Marburg virus transmission by bat-associated flies and fleas in Egyptian fruit bat

16/20

PRF Paweska 16/20

Prabdial-Sing Dr N

National Institute for Communicable Diseases

Pan-genotypic viral genomic analysis in individuals infected with Hepatitis C

15/24

PRF Prabdial-Sing 15/24

Preiser Prof W

Univiversity of Stellenbosch

Diversity and Ecology of Astroviruses in South African Bats

15/25

PRF Preiser 15/25

Preiser Prof W

University of Stellenbosch

Potentially emerging zoonotic viruses in South African bats: Influenza A and Hantaviruses

15/26

PRF Preiser 15/26

Riou Dr C

Univ of Cape Town

Impact of HIV infection on the differentiation of virus-specific CD4+ T helper subsets

14/20

PRF Riou 14/20

Rybicki Prof EP

University of Cape Town

Making reagents for emerging and zoonotic viral pathogens

16/22

PRF Rybicki 16/22

Schafer Dr G

University of Cape Town

The role of cell surface vimentin of HPV16 infection

15/29

PRF Schafer 15/29

Scheepers Dr C

The National Institute of Communicable Diseases

Co-evaluation of a strain-specific antibody lineage and its viral epitope during HIV-1 subtype C infection

16/23

PRF Scheepers 16/23

Scott Dr T

University of the Witwatersrand

Inactivation of Hepatitis B virus in a cell culture infection model using an AAV-delivered CRISPR/Cas system derived from Staphylococcus aureus

15/27

PRF Scott 15/27

Selabe Dr GS

Sefako Makgatho Health Sciences University

Molecular determinants and biological characterization of hepatitis C virus isolates at Dr George Mukhari Academic Hospital

14/22

PRF Selabe 14/22

Selabe Prof SG

Sefako Makgatho Health Sciences University

Characterization of occult and overt hepatitis B virus infection in HIV infected and uninfected patients at the Dr George Mukhari Academic Hospital, Pretoria, South Africa

16/24

PRF Selabe 16/24

Shalekoff Dr S

National Inst for Communicable Diseases

Phenotypic characterization of T Memory Stem cells in infants and adults

14/23

PRF Shalekoff 14/23

Smuts Dr HEM

University of Cape Town

Molecular surveillance of non-poliovirus enterovirus infections in patients with viral meningitis and respiratory illness

15/28

PRF Smuts 15/28

De Assis Rosa Dr D

Univ of the Witwatersrand  (cheque to NICD)

Immunogenetic mechanisms of non-response to hepatitis B vaccine in South African healthworkers

14/10

PRF Suchard 14/10

Suliman Dr T

University of Stellenbosch

Determining the host-range of Neoromicia capensis coronavirus by using viral pseudoparticles

16/25

PRF Suliman 16/25

Van Dijk Prof AA

North-West University

Identification of features of African horsesickness virus outer capsid protein 2 involved in virus replication

15/30

PRF Van Dijk 15/30

Van Staden Dr V

University of Pretoria

The role of African horse sickness virus protein NS4 in the viral life cycle and host immunity

16/26

PRF Van Staden 16/26

Van Zyl Dr WB

Univ of Pretoria

Molecular epidemiology of enteroviruses in South African surface and waste water, with special reference to polioviruses

14/25

PRF Van Zyl 14/25

Van Zyl Dr G

University of Stellenbosch

Characterising the kinetics of HIV-1 persistence, viral evolution and integration sites in children on antiretroviral therapy, in an HIV-1 subtype C setting

15/31

PRF Van Zyl 15/31

Weyer Dr J

The National Institute of Communicable Diseases

Recombinase polymerase assays for rapid and sensitive diagnosis of rabies

16/27

PRF Weyer 16/27

Williamson Prof A

University of Cape Town

Further characterization of genital human papillomaviruses in men and women recruited as couples

15/32

PRF Williamson 15/32

Williamson Prof C

University of Cape Town

HIV-1 superinfection  as a model for vaccine studies

15/33

PRF Williamson 15/33

Woodman Dr Z

University of Cape Town

Investigation into the mechanism whereby bacterial vaginosis increases HIV-1 subtype C infection

16/28

PRF Woodman 16/28

Wose Kinge Dr C

University of the Witwatersrand

Development of stable cell lines for efficient expression of HBV sub-genotype A1

16/29

PRF Wose Kinge 16/29

 

BURSARY

APPLICANT

INSTITUTE

PURPOSE

GRANT NO

PAYMENT REF NO

Adams Ms A

Univ of Cape Town

Analysis and production of HPV virus-like particles and pseudovirions in plants, plant cells and mammalian cells

16/93

PRF Adams 16/93

Amponsah-Dacosta Miss E

Sefako Makgatho Health Sciences University

Molecular characterization of occult hepatitis B virus strains in South Africa

14/99

PRF Amponsah 14/99

Auret Miss JM          

University of Cape Town

Control of respiratory syncytial virus infection by tissue resident T Cell populations

13/68

PRF Auret 13/68

Baloyi Mr I

University of Pretoria

Epidemiology and health risk of rotaviruses in selected surface waters in Gauteng 2013-2016

16/41

PRF Baloyi 16/41

Barakzai Ms I

University of the Free State

HIV drug resistance and viral dynamics in HIV-infectedpaediatric patients in the Free State province

16/87

PRF Barakzai 16/87

Barnard (nee: Malan) Ms K

University of Stellenbosch

Diversity and Ecology of Astroviruses in South African Bats

15/65

PRF Barnard 15/65

Bishop Ms S

North-West University

Recovery of an African horsesickness virus VP2 chimera using reverse genetics

15/43

PRF Bishop 15/43

Bishop Ms S

North-West Univ

Identification of molecular determinants of AHSV involved in attenuation, tropism and virus replication using reverse genetics.

16/102

PRF Bishop 16/102

Blumenthal Ms M

University of Cape Town

The impact of EPHA2 polymorphisms on KSHV infectivity and/or KS prevalence among HIV/AIDS patients in South Africa

16/42

PRF Blumenthal 16/42

Bonnet Ms EH

University of the Free State

Molecular assaysfor zoonotic pathogens

16/30

PRF Bonnet 16/30

Breetzke Ms D

University of Pretoria

Investigating the Natural Reservoir for the Rabies-related Mokola Virus

16/31

PRF Breetzke 16/31

Bruck Miss E

University of Pretoria

Serological and nucleic acid detection of potential zoonotic paramyxoviruses in spill-over and dead-end hosts within SA

16/77

PRF Bruck 16/77

Bulane Ms A

Univ of the Free State

Detection of human papillomavirus types in head and neck squamous cell carcinoma

15/108

PRF Bulane 15/108

Buyse Ms MLR

University of Cape Town

Development of vaccines against beak and feather disease virus

16/62

PRF Buyse 16/62

Castillo Vaca Mr D

University of Pretoria

Characterising the effect of modification to key residues of African horse sickness virus (AHSV) protein on crystalline particles formation and virus core assembly ability

16/75

PRF Castillo 16/75

Ceustermans Miss C

Univ of Pretoria

Epidemiology of arena- and hantaviruses in South African non-volant small mammal populations

16/103

PRF Ceustermans 16/103

Chetty Ms A

Univ of Cape Town

The influence of Nippostrongylus brasiliensis infection on female genital immunity and Herpes simplex virus type II (HSV-2) susceptibility

15/63

PRF Chetty 15/63

Chimukangara Mr B

University of KwaZulu-Natal

Impact of primary HIV-1 drug resistant minority variants on antiretroviral therapy

16/88

PRF Chimukangara 16/88

Cihambanya Dr KL

University of Stellenbosch

Prevalence and risk factors of respiratory infection by respiratory syncytial virus in children at Provincial General Hospital of Bukavu

16/78

PRF Cihambanya 16/78

Conradie Miss A

Univ of Pretoria

The development of a simplified plasmid-based reverse genetics system for African horse sickness virus and its application towards the generation of replication-defective (DISC) vaccine strains

15/85

PRF Conradie 15/85

Dabee Miss S

Univ of Cape Town

Factors affecting susceptibility to HIV infection in the adolescent genital tract

14/48

PRF Dabee 14/48

Damane Ms DR

University of the Free State

Identification of novel human pathogens harboured by rodents

15/44

PRF Damane 15/44

De Beer Mr S

University of Cape Town

Plant-expressed diagnostic proteins and their use for the identification and differentiation of infected and vaccinated animals with Foot and Mouth Disease Virus.

15/45

PRF De Beer 15/45

De Moor Mr W

Univ of Cape Town

Use of self-replicating DNA in vaccine design

14/49

PRF De Moor 14/49

Dennis Ms S

University of Cape Town

The development of plant-produced VLP (virus-like particles) and second generation protein body (PB) vaccines against African horse sickness virus (AHSV)

16/63

PRF Dennis 16/63

Dlamini Ms T

Sefako Makgatho Health Science Univ

Prevalence and genetic diversity of HIV infection in HPV infected and uninfected men who have sex with men residing in the North-West region of Pretoria

16/94

PRF Dlamini 16/94

Do Rosario Yanez Mr R

University of Cape Town

Expression of Candidate Human Papillomavirus Vaccines in Immobilized Plant Cells

15/46

PRF Do Rosarion 15/46

Doolabh Mr D

University of Cape Town

The influence of HIV-1 LTR genotype on latency potential

16/43

PRF Doolabh 16/43

Dzhivhuho Mr GA

Univ of Cape Town

An investigation of the impact of parasitic worm infection on the immunogenicity of candidate HIV vaccines

14/82

PRF Dzhivhuho 14/82

Els Mr JH

University of Cape Town

Identifying algal virus vectors

15/47

PRF Els 15/47

Facey Ms S

University of Pretoria

Recombinase Polymerase Assay for Rapid and Sensitive Diagnosis of Rabies virus

16/32

PRF Facey 16/32

Fearon Mrs S

University of Cape Town

Production of African horse sickness virus (AHSV)-specific antibodies for use as reagents in candidate AHSV vaccine studies

16/79

PRF Fearon 16/79

Folorunso Mr OS

University of the Free State

Rotavirus virus-like particle (RV-VLP) production in yeast

14/100

PRF Folorunso 14/100

Fourie Miss I

Univ of Pretoria

Investigation of the Middelburg alphavirus as a cause of neurological disease in southern Africa.

16/95

PRF Fourie 16/95

Gaelejwe Miss L

University of the Witwatersrand

The evaluation of alternative matrices as part of the sero-molecular surveillance in people most-at-risk for hepatitis C virus

16/80

PRF Gaelejwe 16/80

Geldenhuys Ms L

North-West University

Generation of a set of SA11 expression plasmids for the development of a T7-RNA polymerase- dependant rotavirus reverse genetics system

15/48

PRF Geldenhuys 15/48

Gichana Mr J

University of Stellenbosch

HIV-1 diversity and drug resistance patterns amongst immunocompromised adults and infants in Yaounde Cameroon

16/44

PRF Gichana 16/44

Gunter Mr CJ

University of Cape Town

Porcine circovirus pseudovirion production in Nicotiana benthamiana

16/45

PRF Gunter 16/45

Hanson Miss B

Univ of the Witwatersrand

Gene Editing of Human CCR5 Using an Enhanced CRISPR/SaCas9 Nickase System                      

15/101

PRF Hanson 15/101

Happel Ms A       

University of Cape Town

Role of bacteriophages in development of  bacterial vaginosis in women at high risk for HIV infection

15/64

PRF Happel 15/64

Harris Mr DM

University of the Witwatersrand

Population dynamics in HIV-1 transmitted antiretroviral drug resistance

15/49

PRF Harris 15/49

Hartnady Ms P

Univ of Cape Town

Assessing the biological functionality of secondary structural elements in virus genomes

15/102

PRF Hartnady 15/102

Herd Miss C

University of Pretoria

Evaluating the effects of HIV-1 infection on haematopoietic stem cell colony formation

16/81

PRF Herd 16/81

Humby Miss SA

University of Cape Town

An investigation of the effects of helminthic worm infection on the durability of HIV vaccine-generated immune responses

15/50

PRF Humby 15/50

Huyzers Mr MGJ

North-West Univ

Developing a rotavirus reverse genetics system by combining aspects of other established Reoviridae systems

16/96

PRF Huyzers 16/96

Ismail Ms SD

University of Cape Town

Characterizing the effect of immune activation on the latent HIV reservoir

16/64

PRF Ismail 16/64

Jacobs Ms R

University of Cape Town

Plant-made Zika virus proteins for use in diagnostics assays and potential vaccine candidate

16/46

PRF Jacobs 16/46

Jacobs Miss R

University of the Witwatersrand

Mutational analysis of the NS5A region of hepatitis C genome

16/76

PRF Jacobs 16/76

James Ms C

University of Pretoria

Molecular characterisation of enteroviruses and Sabin-like polioviruses from South African surface water sources

16/33

PRF James 16/33

Jansen V Vuuren Ms L 

North-West University

Investigating the role of the cleavage of African horsesickness virus viral protein 2 by vector and host specific proteases during replication of African horsesickness virus

13/69

PRF JansenVVuuren 13/69

Kariuki Mr SM

University of Cape Town

Phenotypic and genotypic comparison of HIV-1 populations compartmentalized in the blood and semen that potentially influence selection at the transmission bottleneck

16/65

PRF Kariuki 16/65

Katusiime Miss MGK

Univ of Stellenbosch

Characterising the persisting HIV-1 reservoir in early-treated children on long-term suppressive antiretroviral therapy

16/104

PRF Katusiime 16/104

Kehoe Miss K

University of Cape Town

Separation and purification Mucins and Tenascin-C in breast milk of patients and the investigation of the role of Mucins and Tenascin-C in the inhibition of HIV-1

16/82

PRF Kehoe 16/82

Kennedy Ms N

University of the Free State

Host responses to Sindbis virus infection

16/47

PRF Kennedy 16/47

Kerr Miss TJ

Univ of Stellenbosch

Investigating the molecular epidemiology and the evolution of Feline Immunodeficiency Virus (FIV) in African lions (Panthera leo) from South Africa.

14/50

PRF Kerr 14/50

Kiewitz Miss S

University of Stellenbosch

Comprehensive analysis of HIV-1 diversity in different clinics and hospitals in the Eastern Cape Province

15/51

PRF Kiewitz 15/51

Kleinhans Miss B

University of Stellenbosch

Investigating the diversity of paramyxoviruses in South African bat, rodent and shrew species

15/52

PRF Kleinhans 15/52

Kotze Ms A

University of Stellenbosch

Amplification of Neoromicia capensis coronavirus (NeoCoV) cDNA for the construction of a full length infectious clone

16/34

PRF Kotze 16/34

Kriek Mrs J

University of Cape Town

Mechanism of HPV-associated genital wart persistence and recurrence in HIV-infected women

13/71

PRF Kriek 13/71

Kuhlengisa Ms LP

University of Kwa-Zulu Natal

The development and optimization of an HIV-1 p24 antigen assay

16/48

PRF Kuhlengisa 16/48

Lotis Ms K

University of Stellenbosch

HIV testing in cases of Sudden Unexpected Death in Infants (SUDI) at Tygerberg Medico-legal Mortuary

16/35

PRF Lotis 16/35

Mabasa Mr VV

University of Cape Town

Characterisation and histo-blood group antigen binding profiles of South African norovirus genotype II strains

16/49

PRF Mabasa 16/49

Mabvakure Mr BM

The National Institute of Communicable Diseases

Co-evaluation of antibody lineage and their HIV epitopes

16/66

PRF Mabvakure 16/66

Magawai Miss T

University of Cape Town

Bacterial Vaginosis:  Hunting for Bacteriophages targeting vaginal Lactobacilli species

16/39

PRF Magawai 16/39

Makatsa Mr MS

Univ of Cape Town

Investigating Th22 cells as preferential targets for HIV infection

16/105

PRF Makatsa 16/105

Makola Mr RT

Nat Institute for Communicable Dis

Cytoprotective effects of lithium on haemorrhagic fever and immune profiles induced by Ebola virus on Endothelial and RAW 264.7 Macrophage cells

16/106

PRF Makola 16/106

Makoti Ms P

University of the Western Cape

The production of cytokines in human whole blood cultures following exposure to NL63-CoV nucleocapsid protein

16/50

PRF Makoti 16/50

Makua Mr K

Sefako Makgatho Health Science Univ

Investigation of human papillomavirus infection in oral/oropharyngeal mucosa of adults attending Sefako Makgatho Health Sciences University Oral Health Centre, Pretoria

16/97

PRF Makua 16/97

Malivhoho Ms PL

Sefako Makgatho Health Sciences University

Gut microbiota composition in children before and after administration of the rotavirus vaccine at Oukasie Primary Health Care Clinic, Brits, North-West Provnce

16/51

PRF Malivoho 16/51

Maotoana Ms M

University of the Free State

Characterization of T cell responses to the non-structural proteins of the M segment in survivors of Crimean-Congo haemorrhagic fever virus (CCHFV) infection

16/52

PRF Maotoana 16/52

Marie Ms V

University of KwaZulu-Natal

Functional and structural analysis of Gag and protease substitutions in treated and naïve patients infected with HIV-1 subtype C

16/67

PRF Marie 16/67

Masete Miss KV

University of Cape Town

Impact of HIV infectional and transcriptional profile of T cells on viral co-pathogens

16/40

PRF Masete 16/40

Mashishi Miss TL

Sefako Makgatho Health Science Univ

Prevalence of human papillomavirus genotypes from pre-cancerous and cancerous cervical lesions in women attending gynaecology clinic at Dr George Mukhari Academic Hospital

16/98

PRF Mashishi 16/98

Matshazi Mr DM

University of Stellenbosch

Optimising a screening protocol for respiratory infections in Sudden Unexpected Death in Infancy (SUDI) cases admitted to the Tygerberg
Medio-legal Mortuary

15/53

PRF Matshazi 15/53

Matshonyonge Mr F

Sefako Makgatho Health Science Univ

HPV prevalence and factors associated with HPV related precancerous and cancerous lesions in men who have sex with men (MSM) population residing in the North West of Pretoria

16/99

PRF Matshonyonge 16/99

Mbodo Mrs I

University of Cape Town

Investigating the relationship between different hormonal contraceptives and movement of HIV particles in cervical mucous from the genital tract of young South African women

15/66

PRF Mbodo 15/66

McCulloch Mr S

Univ of Pretoria

Disease ecology of Lagos bat virus in South African Rousettus aegyptiacus

14/51

PRF McCulloch 14/51

McQuaid Miss I

University of Cape Town

The Anti-HIV-1 Properties of Human Saliva

15/55

PRF McQuaid 15/55

Mdunyelwa Miss A

Univ of the Witwatersrand

Inhibition of hepatitis B virus using PEGylated helper-dependent adenoviral vectors expressing pri-miRNA’s from MTTR promoter

15/86

PRF Mdunyelwa 15/86

Mellet Ms J

Univ of Pretoria

The susceptibility of hematopoietic stem and progenitor cells to acute and latent HIV-1 infection

16/107

PRF Mellet 16/107

Meno Ms KD

University of Pretoria

Optimisation of norovirus genogroup I (NoV GI) genotyping and characterisation of NoV GI diversity in clinical specimens and sewage
samples

16/36

PRF Meno 16/36

Meyer Ms B

University of Cape Town

Determine the role of subtype B transmission motifs on subtype C Envelope function

16/53

PRF Meyer 16/53

Mezoh Ms G

University of the Witwatersrand

Investigation into the effect of HIV viral proteins on endothelial function in the HIV infected population

16/89

PRF Mezoh 16/89

Mhlekude Mr B

Univ of Cape Town

Defining and comparing the anti-HIV-1 and anti-HIV-2 activities of the native cervical Mucins and equivalent cloned mutants in the contexts of cell-free and cell-associated HIV strains

15/92

PRF Mhlekude 15/92

Mielke  Mr D

Univ of Cape Town

An investigation of the kinetics of ADCC-mediating viral escape and the relationship between neutralizating and ADCC epitopes in early HIV-1 subtype C infection

15/110

PRF Mielke 15/110

Mikasi Mr SG

University of Stellenbosch

Tracking the molecular epidemiology and resistance patterns of HIV-1 in the rural Western Cape province of South Africa

15/56

PRF Mikasi 15/56

Mnyandu Mr NZ

Univ of the Witwatersrand

Efficacy of recombinant AAV expressing anti_HBV Pri-miRs from a liver-spesific promoter

15/103

PRF Mnyandu 15/103

Moliki Mr JM

University of Cape Town

The Role of Pro-inflammatory Cytokines and Peptide Hormones in the Modulation of HIV Pathogenesis in the Female Genital Tract

15/67

PRF Moliki 15/67

Moodie Ms M

University of the Witwatersrand

Sequential adeno-associated virus -delivered HIV-1 envelope glycoproteins as novel vaccine immunogens

16/54

PRF Moodie 16/54

Moshoette Mr T

University of the Witwatersrand

Engineering bispecific antibody iMab-Cap256 targeting HIV-1 subtype C

16/83

PRF Moshoette 16/83

Motlou Ms TP

University of Pretoria

Epidemiology of Shuni virus in horses South Africa

16/92

PRF Motlou 16/92

Moyo Miss T

Univ of Cape Town

Narrowly neutralising anti-HIV-1 antibodies directed against targets of broadly neutralising antibodies: What can they tell us about vaccine priorities?

14/83

PRF Moyo 14/83

Muilwijk Miss M

University of Pretoria

The assessment of sewage treatment efficacy through the detection and characterisation of human enteroviruses

15/57

PRF Muilwijk 15/57

Munsamy Miss Y

University of the Free State

Characterisation of human papilloma viruses associated with head and neck cancers

15/68

PRF Munsamy 15/68

Murahwa Mr AT

Univ of Cape Town

Characterization of genital human papilomaviruses in HIV-1 concordant and discordant heterosexual couples

15/69

PRF Murahwa 15/69

Murugan Mr BD

University of Cape Town

Proteomic Characterisation of the Mechanisms of HIV-associated Neuronal Degeneration and its Impact on Neuronal Development in Childhood

16/90

PRF Murugan 16/90

Nekhwevha Mr K

University of the Witwatersrand

Molecular characterization and genotyping of hepatitis B virus (HBV) from Sudanese End Stage Renal Disease (ESRD) patients with Overt and Occult HBV infection

16/84

PRF Nekhwevha 16/84

Ngomane Ms T

Sefako Makgatho Health Science Univ

Genetic diversity of group a rotavirus strains circulating in pigs from five provinces in South Africa

15/104

PRF Ngomane 15/104

Nhundu Mr TJ

University of Cape Town

Mechnisms of glucocorticoid ori-inflammatory effects: croasstalk, synergy and implications in HIV-1 acquisition

16/56

PRF Nhundu 16/56

Njenda Mr DT

University of Stellenbosch

Role of adaptive changes and co-evolution of HIV-1C protease cleavage site mutations for protease inhibitor resistance and viral fitness

16/68

PRF Njenda 16/68

Nkambule Ms H

University of Pretoria

The detection and characterization of coronaviruses in insectivorous bats and small non-volant mammals of the Meletse area, Limpopo and Irene
caves, Gauteng

16/55

PRF Nkambule 16/55

Nkwinika Ms VV

Sefako Makgatho Health Sciences University

Human papillomavirus infections in anorectal cancer at the Dr George Mukhari Academic Hospital from 2005-2012

16/37

PRF Nkwinika 16/37

Nyangahu Mr DD

University of Cape Town

Effect of maternal antibiotic treatment during pregnancy and breastfeeding on infant gut microbiome and immunity to Respiratory syncytial viral infections in mice.

15/70

PRF Nyangahu 15/70

Obasa Mr AEA

University of Stellenbosch

Characterization of new complex HIV-1 Circulating Recombinant Forms (CRFs) and Unique Recombinant Forms (URFs) identified in South Africa

15/59

PRF Obasa 15/59

O’Connor Mr S

Univ of Cape Town

Production of foot and mouth disease virus vaccine candidate in plants

15/87

PRF O’Connor 15/87

Omondi Miss FMA

Univ of Cape Town

Investigating the effect of HIV on the immune response to respiratory viruses

15/88

PRF Omondi 15/88

Onywera Mr DH

Univ of Cape Town

The vaginal microbiota of black South African women and associations with human papillomavirus (HPV) infection

14/53

PRF Onywera 14/53

Pereira Mr R

Univ of the Witwatersrand

Immunogenicity testing of HIV-1 envelope glycoprotein vaccine complexes (Env-2dCD4S60C) in chinese origin rhesus macaques

16/108

PRF Pereira 16/108

Pietersen Ms I

University of Cape Town

Production of Bovine papillomavirus VLP vaccine in plants

16/58

PRF Pietersen 16/58

Poovan Miss K

University of Stellenbosch

Potentially emerging zoonotic viruses in South African bats: Influenza A and Hantaviruses

15/72

PRF Poovan 15/72

Rachida Ms S

University of Pretoria

Genetic assessment of infectious hepatitis A virus strains detected in selected water sources in South Africa

16/69

PRF Rachida 16/69

Rakaki Ms ME

Univ of the Free State

Expression of rotavirus VP6 capsid protein derived from a codon optimized open reading frame in various yeasts.

16/100

PRF Rakaki 16/100

Rakau Ms K

Sefako Makgatho Health Sciences University

Molecular characterization of rotavirus infections in children attendinf Dr George Mukhari Academic Hospital and Oukasie Primary Health Care and their association with Histo blood group antigen profiles

15/89

PRF Rakau 15/89

Ramulongo Ms TD

University of Pretoria

Immune refocusing of a SAT2 foot-and-mouth disease vaccine strain through dampening of antigenic regions

16/70

PRF Ramulongo 16/70

Richardson Ms SI

The National Institute of Communicable Diseases

Properties of antiviral antibodies in natural HIV infection and those induced by vaccination

15/93

PRF Richardson 15/93

Ruhanya Mr V

Univ of Stellenbosch

In depth analysis of HIV-1 diversity and inflammatory makers in different cell compartmens in HIV associated neurocognitive disorders (HAND)

16/109

PRF Ruhanya 16/109

Saayman Ms JE

University of Stellenbosch

Identification and assessment of viral myocardial pathogens in cases of sudden unexpected death in infants (SUDI) at Tygerberg Medico-legal Mortuary in the Western Cape

16/59

PRF Saayman 16/59

Sampson Miss N 

Univ of Stellenbosch

Emerging coronaviruses in southern African bats

14/54

PRF Sampson 14/54

Sander Mr W

Univ of the Free State

Investigation into the effect of fatty acids on the yield of infectious rotavirus

15/105

PRF Sander 15/105

Scott Mr D

University of Cape Town

Potential role of the Human papillomavirus type 18 E6 and E7 oncogenes in cervical inflammation and cancer

14/97

PRF Scott 14/97

Sheward Mr D

Univ of Cape Town

Understanding the antibody response of HIV: lessons for vaccine design from natural infection

16/71

PRF Sheward 16/71

Sibiya Ms LP

University of Pretoria

Epidemiology of paramyxoviruses in rodents, shrews, sengi and bats found in Meletse area, Limpopo and Irene area Gauteng

16/60

PRF Sibiya 16/60

Simelane Mr D

University of the Witwatersrand

Expression of envelope proteins by pre-S1/pre-S2 deletion mutants of HBV isolated from southern African HIV-positive patients

15/60

PRF Simelane 15/60

Singh Miss P

Univ of the Witwatersrand

Generation and characterization of hepatitits B stable cell lines that constitutively produce infectious viral particles

15/106

PRF Singh 15/106

Sondlane Ms TH

Sefako Makgatho Health Sciences University

Molecular characterisation, serological profiling, and risk factor analysis of hepatitis B virus infection in healthcare workers from Gauteng and Mpumalanga provinces, South Africa

15/73

PRF Sondlane 15/73

Tamandjou Tchuem Miss CR

University of Stellenbosch

Hepatitis B virus mother-to-Child-transmission in Namibia: transmission dynamics and possibilities for elimination

15/74

PRF Tamandjou 15/74

Tanov Mr E

Univ of the Western Cape

Identification and ranking of pervasive secondary structures in positive-sense single-stranded ribonucleic acid viral genomes

14/55

PRF Tanov 14/55

Terblanche Mr GID

University of the Free State

Surveillance of medically important mosquito-borne arboviruses in the Free State Province, South Africa

16/61

PRF Terblanche 16/61

Theart Mr LJC

North-West Univ

Expression and optimization of assembly of rotavirus VP2,6,4 & VP7 VLPs in both bacterial and baculovirus expression systems

16/101

PRF Theart 16/101

Tipih Mr T

Univ of the Free State

Immunogenicity of alphavirus based replicon for CCHFV

14/85

PRF Tipih 14/85

Van Coller Ms A

University of Stellenbosch

Relationship of pro-inflammatory cytokines to changes in dendritic cell numbers and phenotype in chronic HIV-1 infection

16/38

PRF Van Coller 16/38

Van Dorsten-Wakabayashi Mrs RT

The National Institute of Communicable Diseases

Exploring the potential of engineered antibodies to prevent HIV cell-cell transmission

16/72

PRF Van Dorsten-W 16/72

Van Der Merwe Mr J

North-West University

Exploring the use of cellular RNA polymerase I and II promoters for the development of rotavirus reverse genetics system

15/61

PRF VDMerwe 15/61

Veerapen Miss VP

Univ of Cape Town

Expression of foot- and- mouth disease virus (FMDV) virus-like-particles (VLPs) in Nicotiana benthamiana

15/107

PRF Veerapen 15/107

Viljoen Ms N 

University of the Free State

Innate immune signalling induced in vitro by Crimean-Congo haemorrhagic fever virus proteins

15/75

PRF Viljoen 15/75

Wall Miss G

University of Pretoria 

Characterisation of the role of non-structural protein NS4 in African horse sickness virus replication

15/76

PRF Wall 15/76

Wayland Miss J

Univ of Cape Town

Transient expression of PrM and E proteins of West Nile Virus in plants as a viable, low-cost method for reagent development for diagnostics

16/110

PRF Wayland 16/110

Wickham Miss C

University of Pretoria

Transcriptional analysis of the host response to HIV-1 infection in CD4+ T lymphocytes and macrophages

16/85

PRF Wickham 16/85

Williams Mr ME

University of Cape Town

An investigation of a neuro-inflammatory profile of aging in HIV-associated neurocognitive disorders

16/91

PRF Williams 16/91

Youbi Mrs ME

Univ of the Witwatersrand / NICD

Analysis of the NS3 protease gene across HCV genotypes in treatment naïve individuals

15/90

PRF Youbi 15/90

Zitha Ms T

University of the Witwatersrand

Molecular characterization and genotyping of hepatitis C virus from Sudanese End-stage Renal Disease Patients

16/86

PRF Zitha 16/86

 

JAMES GEAR INTERNATIONAL FELLOWSHIP – 2017

APPLICANT

INSTITUTE

PURPOSE

GRANT NO

PAYMENT REF NO

Kgatle Dr MM

University of Cape Town

Project:  Characterisation of de novo DNA methyltransferase 3A and 3B mutants, and elucidation of their mechanisms in action

16/111

PRF Kgatle 16/111